Kaizen Advanced, Individualized TMS


What is Transcranial Magnetic Simulation (TMS)?


Transcranial Magnetic Stimulation (TMS) is a proven treatment for brain disorder symptoms such as depression and anxiety, migraines, impulsiveness, and brain fog. TMS has also been found to be effective for treating symptoms of Alzheimer’s disease and Post-Concussive Disorder.

TMS is FDA-Approved for treatment-resistant depression and CE-Approved for Alzheimer’s disease, Autism, Bipolar Disorder, chronic pain, Parkinson’s disease, PTSD, Schizophrenia, and smoking cessation.


Transcranial Magnetic Stimulation (TMS)TMS is non-invasive. A treatment coil is placed against the head, where it emits short bursts of electromagnetic currents to targeted regions of the brain. The TMS magnetic field, which is similar to that produced by a magnetic resonance imaging (MRI) machine, alters neural activity to establish a “new normal.”

Neuroplasticity, the brain’s remarkable ability to rebuild and expand neural connections, allows TMS to strengthen disrupted networks.


TMS Protocol


one symptom_one target


Traditional TMS Targeting

Until recently, TMS has relied on generalized knowledge of brain architecture to stimulate a single target – the prefrontal cortex, which is correlated with depression. To treat the area, the TMS technician would find the motor cortex and then stimulate the region 5 cm in front of it.



Kaizen Advanced, Personalized TMS Targeting

Years of experience led Kaizen specialists to expand the TMS protocol beyond the traditional targeting methods. Rather than use the 5 cm rule to target a single, broad area of the brain associated with depression, Kaizen located and treated multiple sites correlated with additional symptoms, such as depression-related anxiety and impulsivity.

Kaizen Individualized TMS is able to achieve this new level of precision due to three novel components:

1.    Comprehensive Evaluation –

Patients receive a comprehensive assessment by one or more of our multidisciplinary specialists in Neuropsychiatry, Neurology, and Neuropsychology to identify areas of the brain that will benefit from TMS treatments. These clinicians have extensive training and experience with brain disorders, and thus are uniquely qualified to diagnose symptoms and accurately locate treatment areas.

2.    3D Neural Network Mapping –

Harvard Neuropsychiatrist and Kaizen Advisor Shan Siddiqi developed a novel method for narrowing treatment areas down to precise coordinates in the brain. Using fMRI, a form of imaging that looks at changes in blood flow, he and his team created 3D maps of an individual’s complete brain circuitry to identify exact locations linked to specific symptoms. Kaizen Brain Center was the first clinic worldwide to use the 3D Neural Network Mapping tool.


The 3D neural maps show the complex neural network of one individual. In this example, yellow regions are part of the memory network. The brain’s memory center (white circle) is too deep to reach with TMS, so instead Kaizen specialists target the connected region (black circle) closer to the brain’s surface.

neuronavigation, TMS, 3D brain map3.    Neuronavigation –

Kaizen providers use a stereotactic positioning tool (the type used to facilitate brain surgery) to guide TMS current to the precise coordinates identified using the Neural Network Mapping tool.

Neuronavigation technology visualizes the client’s brain based on MRI or fMRI data so that the technician can move the coil to the desired brain structure and correctly position it for TMS treatment.


Can all physicians use TMS?

While any physician may perform TMS treatments, only clinicians highly specialized in brain architecture and disorders can target symptoms and sites consistently and accurately.

Why haven’t I heard of TMS?

TMS has been around for years, but the treatment was relatively unknown until recent advances greatly improved treatment accuracy and versatility. TMS is also becoming more familiar among physicians and patients as the body of evidence showing its effectiveness grows.

How much does Kaizen Advanced fMRI-Guided TMS cost?

Depending on the Personalized Treatment Plan, fMRI multisite TMS cost is similar to that of traditional TMS. fMRI imaging takes place at an outside imaging center and incurs an additional cost. Kaizen’s Patient Coordinator will provide comprehensive pricing information.

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